ORIGINAL USES (ON-LABEL)
Various bacterial infections in the lung, eye, sinuses, skin, and skin structure.
BRAND NAME Ciloxan, Cipro, Cipro XR
DRUG CLASS
Antibiotic (quinolone)
DESCRIPTION
This drug is used to treat infections. It works by interfering with cellular enzymes, stopping the activity of DNA.
POTENTIAL SIDE EFFECTS
Dizziness, nausea, diarrhea, various blood disorders such as anemia, tremors, confusion, depression, nervousness, agitation, anxiety.
CAUTIONS
Report to your doctor if you experience pain, inflammation or rupture of a tendon. Rest and refrain from exercise until you see a doctor. Tendon rupture can occur during or after therapy with this drug.
Stop the medication at the first sign of a rash.
Prolonged use may cause superinfection.
May aggravate symptoms of myasthenia gravis.
Inform your doctor if serious, persistent diarrhea develops.
DRUG INTERACTIONS
Iron, zinc, calcium, magnesium, aluminum, corticosteroids (increase risk of tendon rupture), antacids, electrolyte supplements, quinapril, sucralfate, certain antiarrhythmics, didanosine formulations (chewable/buffered tablets and pediatric powder for oral suspension), theophyllines, antacids, cyclosporine, cimetidine
FOOD INTERACTIONS
Dairy products or calcium-fortified juices. Serum caffeine levels may be increased.
HERBAL INTERACTIONS
Dong quai, St. John’s wort
PREGNANCY AND BREAST-FEEDING CAUTIONS
FDA Pregnancy Risk Category C. May be excreted in breast milk. Do not use during breast-feeding.
SPECIAL INFORMATION
Extended release tablets cannot be crushed, split, or chewed. Take entire prescription even if feeling better. Maintain adequate hydration (2 to 3 L/day of fluids) to avoid concentrated urine and crystal formation.
May cause increased sensitivity to sunlight; use sunblock, wear protective clothing and dark glasses. Report immediately any signs of rash, joint or back pain, difficulty breathing, easy bruising or bleeding, inflammation, or rupture of tendon.
