NEWLY DISCOVERED USES (OFF-LABEL)
Male infertility
ORIGINAL USES (ON-LABEL)
Treatment of ovulatory failure in patients desiring pregnancy
BRAND NAME Clomid, Serophene
DRUG CLASS
Ovulation stimulator
DESCRIPTION
This drug induces ovulation by stimulating the release of hormones.
POTENTIAL SIDE EFFECTS
Hot flashes, ovarian enlargement, blood clots, mental depression, headache, breast enlargement (males), breast discomfort (females), abnormal menstrual
flow, ovarian cyst formation, distention, bloating, nausea, vomiting, liver toxicity, blurring of vision, double vision, visual floaters, visual afterimages.
CAUTIONS
Not for use if you have liver disease, abnormal uterine bleeding, enlargement or development of ovarian cyst, uncontrolled thyroid or adrenal dysfunction, pituitary tumor, or pregnancy.
Multiple pregnancies, blurring or other visual symptoms, over stimulation of ovaries, and abdominal pain can occur with the use of this medication.
DRUG INTERACTIONS
Danazol, estradiol
FOOD INTERACTIONS
Unknown
HERBAL INTERACTIONS
Unknown
PREGNANCY AND BREAST-FEEDING CAUTIONS
FDA Pregnancy Risk Category X. Excretion in breast milk unknown. Not for use during breast-feeding.
SPECIAL INFORMATION
When used for female ovulation stimulation, the majority of patients who ovulate will do so after the first course of therapy. If ovulation does not occur after three courses of therapy, the need for this drug should be re-evaluated. Notify your doctor if bloating, stomach or pelvic pain, blurred vision, jaundice, hot flushes or vomiting occur.
